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ATC Group: B01AX01 Defibrotide

Anatomical Therapeutic Chemical Classification System

Translations

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Defibrotide

Hierarchical Position

Active Ingredients

Chemical substance
Description

Defibrotide is an oligonucleotide mixture with demonstrated antithrombotic, fibrinolytic, anti-adhesive and anti-inflammatory actions. The mechanism of action is multifactorial. It primarily acts through reducing excessive endothelial cell (EC) activation (endothelial dysfunction), modulating endothelial homeostasis as well as restoring thrombo-fibrinolytic balance.