The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | D | Dermatologicals | |
| 2 | D10 | Anti-acne preparations | |
| 3 | D10B | Anti-acne preparations for systemic use | |
| 4 | D10BA | Retinoids for treatment of acne | |
| 5 | D10BA01 | Isotretinoin |
The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.
| Route | Amount |
|---|---|
| ORAL - Oral | 30 mg |
| Active Ingredient | Description | |
|---|---|---|
| Isotretinoin |
Isotretinoin is a stereoisomer of all-trans retinoic acid (tretinoin). The exact mechanism of action of isotretinoin has not yet been elucidated in detail, but it has been established that the improvement observed in the clinical picture of severe acne is associated with suppression of sebaceous gland activity and a histologically demonstrated reduction in the size of the sebaceous glands. Furthermore, a dermal anti-inflammatory effect of isotretinoin has been established. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| ISOTRETINOIN Capsules, soft | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ORATANE Soft capsule | Medicines and Medical Devices Safety Authority (NZ) | MPI, EU: SmPC | |
| ROACCUTANE Capsule, soft | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
