The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | G | Genito urinary system and sex hormones | |
| 2 | G03 | Sex hormones and modulators of the genital system | |
| 3 | G03X | Other sex hormones and modulators of the genital system | |
| 4 | G03XC | Selective estrogen receptor modulators |
| Code | Title | |
|---|---|---|
| G03XC01 | Raloxifene | |
| G03XC02 | Bazedoxifene | |
| G03XC05 |
| Active Ingredient | Description | |
|---|---|---|
| Bazedoxifene |
|
|
| Ospemifene |
Ospemifene and its major metabolite have an oestrogen like effect in the vagina increasing the cellular maturation and mucification of the vaginal epithelium. Ospemifene’s biological actions are mediated through the binding of ospemifene and its major metabolite to oestrogen receptors leading to activation of some oestrogenic pathways (agonism) and blockade of other (antagonism). |
|
| Raloxifene |
As a selective oestrogen receptor modulator (SERM), raloxifene has selective agonist or antagonist activities on tissues responsive to oestrogen. It acts as an agonist on bone and partially on cholesterol metabolism (decrease in total and LDL-cholesterol), but not in the hypothalamus or in the uterine or breast tissues. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| CONBRIZA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| EVISTA Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| EVISTA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| OPTRUMA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| SENSHIO Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
