ATC Group: H01AA ACTH

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of H01AA in the ATC hierarchy

Level
Code
Title
1
Systemic hormonal preparations, excl. Sex hormones and insulins
2
Pituitary and hypothalamic hormones and analogues
3
Anterior pituitary lobe hormones and analogues
4
H01AA
ACTH

Group H01AA contents

Code
Title
Corticotropin
Tetracosactide

Active ingredients in H01AA

Active Ingredient
Description

Corticotropin is a polypeptide hormone produced and secreted by the pituitary gland. Corticotropin acts through the stimulation of cell surface ACTH receptors, which are primarily located on the adrenocortical cells. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens).

Tetracosactide acetate consists of the first 24 amino acids occurring in the natural corticotropic hormone (ACTH) sequence and displays the same physiological properties as ACTH. In the adrenal cortex, it stimulates the biosynthesis of glucocorticoids, mineralocorticoids, and, to a lesser extent, androgens, which explains its therapeutic effect in conditions responsive to glucocorticoid treatment.

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