The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | L | Antineoplastic and immunomodulating agents | |
| 2 | L01 | Antineoplastic agents | |
| 3 | L01A | Alkylating agents | |
| 4 | L01AB | Alkyl sulfonates | |
| 5 | L01AB01 | Busulfan |
| Active Ingredient | Description | |
|---|---|---|
| Busulfan |
Busulfan is a potent cytotoxic agent and a bifunctional alkylating agent. In aqueous media, release of the methanesulphonate groups produces carbonium ions which can alkylate DNA, thought to be an important biological mechanism for its cytotoxic effect. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| BUSILVEX Concentrate for solution | European Medicines Agency (EU) | MPI, EU: SmPC | |
| BUSULFAN Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| BUSULFEX Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| MYLERAN Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
