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Busulfan

Also known as: Busulphan

Description

Busulfan is a potent cytotoxic agent and a bifunctional alkylating agent. In aqueous media, release of the methanesulphonate groups produces carbonium ions which can alkylate DNA, thought to be an important biological mechanism for its cytotoxic effect.

Medicine classification

ATC Code
Title
Class
L01AB01
Busulfan
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AB Alkyl sulfonates

Medicines

Drug
Countries

Austria France Lithuania Netherlands Spain

Singapore United States

Singapore

Product monographs

Monograph
Type
Country
BUSULFEX Solution for injection
MPI, US: SPL/PLR
US
BUSULFAN Film-coated tablet
MPI, EU: SmPC
UK
MYLERAN Film-coated tablet
MPI, US: SPL/Old
US
BUSILVEX Concentrate for solution
MPI, EU: SmPC