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ATC Group: L01EK01 Axitinib

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
L
Antineoplastic and immunomodulating agents
2
L01
Antineoplastic agents
3
L01E
Protein kinase inhibitors
4
L01EK
Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors
5
L01EK01
Axitinib

Active Ingredients

Chemical substance
Description
Axitinib

Axitinib is a potent and selective tyrosine kinase inhibitor of vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2 and VEGFR-3. These receptors are implicated in pathologic angiogenesis, tumour growth, and metastatic progression of cancer. Axitinib has been shown to potently inhibit VEGF-mediated endothelial cell proliferation and survival.

Monographs

Monograph
Type
Country
INLYTA
MPI, EU: SmPC
UK
INLYTA Film-coated tablet
MPI, EU: SmPC