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ATC Group: L01EK01 Axitinib

Anatomical Therapeutic Chemical Classification System

Translations

Language
Translation
  English
Axitinib

Hierarchical Position

Active Ingredients

Chemical substance
Description

Axitinib is a potent and selective tyrosine kinase inhibitor of vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2 and VEGFR-3. These receptors are implicated in pathologic angiogenesis, tumour growth, and metastatic progression of cancer. Axitinib has been shown to potently inhibit VEGF-mediated endothelial cell proliferation and survival.

Monographs

Monograph
Type
Country
MPI, EU: SmPC
UK