ATC Group: L02AE05 Histrelin

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of L02AE05 in the ATC hierarchy

Level Code Title
1 L Antineoplastic and immunomodulating agents
2 L02 Endocrine therapy
3 L02A Hormones and related agents
4 L02AE Gonadotropin releasing hormone analogues
5 L02AE05

Defined daily dose

The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.

Route Amount
PAREN - Parenteral 137 mg

Active ingredients in L02AE05

Active Ingredient Description
Histrelin

Histrelin is a gonadotropin releasing hormone (GnRH) agonist and an inhibitor of gonadotropin secretion when given continuously. It is indicated for the treatment of children with central precocious puberty (CPP). However, continuous administration of histrelin acetate causes a reversible down-regulation of the GnRH receptors in the pituitary gland and desensitization of the pituitary gonadotropes.

Related product monographs

Title Information Source Document Type  
VANTAS Implant FDA, National Drug Code (US) MPI, US: SPL/PLR

Medicines in this ATC group

United States (US)

South Africa (ZA)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.