Chemical formula: C₆₆H₈₆N₁₈O₁₂ Molecular mass: 1,443.632 g/mol PubChem compound: 56927879
Histrelin is a gonadotropin releasing hormone (GnRH) agonist and an inhibitor of gonadotropin secretion when given continuously. It is indicated for the treatment of children with central precocious puberty (CPP). However, continuous administration of histrelin acetate causes a reversible down-regulation of the GnRH receptors in the pituitary gland and desensitization of the pituitary gonadotropes.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L02AE05 | L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02A Hormones and related agents → L02AE Gonadotropin releasing hormone analogues | |
Histrelin is an active ingredient of these brands:
United States (US)
South Africa (ZA)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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