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ATC Group: L04AA06 Mycophenolic acid

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
L
Antineoplastic and immunomodulating agents
2
L04
Immunosuppressants
3
L04A
Immunosuppressants
4
L04AA
Selective immunosuppressants
5
L04AA06
Mycophenolic acid

Active Ingredients

Chemical substance
Description
Mycophenolate mofetil

Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA). MPA is a potent, selective, uncompetitive and reversible inhibitor of inosine monophosphate dehydrogenase, and therefore inhibits the de novo pathway of guanosine nucleotide synthesis without incorporation into DNA.

Mycophenolic acid

Mycophenolic acid is a potent, selective, uncompetitive and reversible inhibitor of inosine monophosphate dehydrogenase, and therefore inhibits the de novo pathway of guanosine nucleotide synthesis without incorporation into DNA. Mycophenolic acid has more potent cytostatic effects on lymphocytes than on other cells and is indicated in combination with ciclosporin and corticosteroids for the prophylaxis of acute transplant rejection in adult patients receiving allogeneic renal transplants.

Monographs

Monograph
Type
Country
CELLCEPT Capsules
MPI, EU: SmPC
CELLCEPT Powder for concentrate for solution for infusion
MPI, EU: SmPC
MYFORTIC Gastro-resistant tablet
MPI, EU: SmPC
UK