Chemical formula: C₁₇H₂₀O₆ Molecular mass: 320.337 g/mol PubChem compound: 446541
Mycophenolic acid is a potent, selective, uncompetitive and reversible inhibitor of inosine monophosphate dehydrogenase, and therefore inhibits the de novo pathway of guanosine nucleotide synthesis without incorporation into DNA. Mycophenolic acid has more potent cytostatic effects on lymphocytes than on other cells and is indicated in combination with ciclosporin and corticosteroids for the prophylaxis of acute transplant rejection in adult patients receiving allogeneic renal transplants.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L04AA06 | Mycophenolic acid | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AA Selective immunosuppressants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MYFORTIC Gastro-resistant tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Mycophenolic acid is an active ingredient of these brands:
United States (US)
Australia (AU)
Austria (AT)
Canada (CA)
Croatia (HR)
Cyprus (CY)
France (FR)
Germany (DE)
Hong Kong (HK)
Israel (IL)
Lithuania (LT)Malta (MT)
Mexico (MX)
Netherlands (NL)
Romania (RO)
Singapore (SG)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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