ATC Group: M03AC Other quaternary ammonium compounds

Anatomical Therapeutic Chemical Classification System

Hierarchical position in ATC classification

Level
Code
Title
1
Musculo-skeletal system
2
Muscle relaxants
3
Muscle relaxants, peripherally acting agents
4
M03AC
Other quaternary ammonium compounds

ATC group contents

Code
Title
Pancuronium
Gallamine
Vecuronium
Atracurium
Hexafluronium
Pipecuronium bromide
Doxacurium chloride
Fazadinium bromide
Rocuronium bromide
Mivacurium chloride
Cisatracurium

Active ingredients

Active Ingredient
Description

Atracurium besilate is a non-depolarising neuromuscular blocking agent with an intermediate duration of action, administered intravenously to produce skeletal muscle relaxation.

Cisatracurium is an intermediate-duration, non-depolarising benzylisoquinolinium skeletal muscle relaxant.

Pancuronium produces pharmacologic effects similar to those of other non-depolarising neuromuscular blocking agents. The drug may produce an increase in heart rate which appears to result from a direct blocking effect on the acetylcholine receptors of the heart. Pancuronium causes little or no histamine release and no ganglionic blockade and therefore does not cause hypotension or bronchospasm.

Rocuronium bromide is a fast onset, intermediate acting non-depolarising neuromuscular blocking agent, possessing all of the characteristic pharmacological actions of this class of medicinal products (curariform agents). It acts by competing for nicotinic cholinoceptors at the motor end-plate.

Vecuronium is a non-depolarising neuromuscular blocking agent. Vecuronium blocks the transmission process between the motor nerve-ending and striated muscle by binding competitively with acetylcholine to the nicotinic receptors located in the motor end-plate region of striated muscle.

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