Cisatracurium Other names: Cisatracurium besilate

Chemical formula: C₆₅H₈₂N₂O₁₈S₂  Molecular mass: 929.16 g/mol  PubChem compound: 62886

Active ingredient description

Cisatracurium is an intermediate-duration, non-depolarising benzylisoquinolinium skeletal muscle relaxant. Cisatracurium binds to cholinergic receptors on the motor end-plate to antagonise the action of acetylcholine, resulting in a competitive block of neuromuscular transmission. This action is readily reversed by anti-cholinesterase agents such as neostigmine or edrophonium.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
M03AC11 Cisatracurium M Musculo-skeletal system → M03 Muscle relaxants → M03A Muscle relaxants, peripherally acting agents → M03AC Other quaternary ammonium compounds
Discover more medicines within M03AC11

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CISATRACURIUM Solution for injection/infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
NIMBEX Solution for injection / infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 96946-41-7
DrugBank Drug: DB00565
PubChem Compound: 62886
RxNorm Ingredient: 319864
SNOMED-CT Concept: 372495006
Cisatracurium (substance)
UNII Identifier: 80YS8O1MBS
CISATRACURIUM BESYLATE
UNII Identifier: QX62KLI41N
CISATRACURIUM

Medicines

Cisatracurium is an active ingredient of these brands:

United States (US)

Austria (AT)

Cyprus (CY)

Ecuador (EC)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Lithuania (LT)

Mexico (MX)

Netherlands (NL)

Poland (PL)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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