ATC Group: N01AX14 Esketamine

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N01AX14 in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N01 Anesthetics
3 N01A Anesthetics, general
4 N01AX Other general anesthetics
5 N01AX14 Esketamine

Active ingredients in N01AX14

Active Ingredient Description
Esketamine

Esketamine, the S-enantiomer of racemic ketamine, is a non-selective, non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, an ionotropic glutamate receptor. Through NMDA receptor antagonism, esketamine produces a transient increase in glutamate release. Restoration of dopaminergic neurotransmission in brain regions involved in the reward and motivation, and decreased stimulation of brain regions involved in anhedonia, may contribute to the rapid response.

Medicines in this ATC group

Austria (AT)

Croatia (HR)

Estonia (EE)

Finland (FI)

Netherlands (NL)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.