The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | N | Nervous system | |
| 2 | N04 | Anti-parkinson drugs | |
| 3 | N04A | Anticholinergic agents |
| Code | Title | |
|---|---|---|
| N04AA | Tertiary amines | |
| N04AB | Ethers chemically close to antihistamines | |
| N04AC | Ethers of tropine or tropine derivatives |
| Active Ingredient | Description | |
|---|---|---|
| Benzatropine |
Benzatropine possesses both anticholinergic and antihistaminic effects, although only the former have been established as therapeutically significant in the management of parkinsonism. |
|
| Biperiden |
Biperiden is a predominantly centrally acting anti-cholinergic. It has a peripheral effect, which is low in comparison to atropine. Biperiden binds competitively to peripheral and central muscarinic receptors (primarily M1). |
|
| Bornaprine |
|
|
| Mazaticol |
|
|
| Orphenadrine |
Orphenadrine, which is a congener of diphenhydramine without sharing its soporific effect, is an anti-muscarinic agent. Orphenadrine is used as the hydrochloride in the symptomatic treatment of Parkinsonism. |
|
| Profenamine |
|
|
| Trihexyphenidyl |
Trihexyphenidyl is an anticholinergic agent. It is an antispasmodic drug which exerts a direct inhibitory effect on the parasympathetic nervous system. It diminishes salivation, increases the heart rate, dilates the pupils and reduces spasm of smooth muscle. |
|
| Tropatepine |
|
| Title | Information Source | Document Type | |
|---|---|---|---|
| AKINETON Solution for injection | European Medicines Agency (EU) | MPI, EU: SmPC | |
| AKINETON Tablets | European Medicines Agency (EU) | MPI, EU: SmPC | |
| COGENTIN Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| KEMADRIN Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| KEMADRIN Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PHENERINE Sugar-coated tablet | Health Products Regulatory Authority (ZA) | MPI, Generic |
