Chemical formula: C₁₈H₂₃NO Molecular mass: 269.381 g/mol PubChem compound: 4601
Orphenadrine, which is a congener of diphenhydramine without sharing its soporific effect, is an anti-muscarinic agent. Orphenadrine is used as the hydrochloride in the symptomatic treatment of Parkinsonism.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M03BC01 | Orphenadrine (citrate) | M Musculo-skeletal system → M03 Muscle relaxants → M03B Muscle relaxants, centrally acting agents → M03BC Ethers, chemically close to antihistamines |
| N04AB02 | Orphenadrine (chloride) | N Nervous system → N04 Anti-parkinson drugs → N04A Anticholinergic agents → N04AB Ethers chemically close to antihistamines |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ORPHENADRINE CITRATE Extended release tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| ORPHENADRINE HYDROCHLORIDE Oral solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Orphenadrine is an active ingredient of these brands:
United States (US)
Austria (AT)
Brazil (BR)
Canada (CA)
Cyprus (CY)
Ecuador (EC)
Hong Kong (HK)
Israel (IL)
Malta (MT)Mexico (MX)
Nigeria (NG)Romania (RO)
Singapore (SG)
South Africa (ZA)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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