ATC Group: N06AF Monoamine oxidase inhibitors, non-selective

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N06AF in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N06 Psychoanaleptics
3 N06A Antidepressants
4 N06AF Monoamine oxidase inhibitors, non-selective

Group N06AF contents

Code Title
N06AF01 Isocarboxazid
N06AF02 Nialamide
N06AF03 Phenelzine
N06AF04 Tranylcypromine
N06AF05 Iproniazide
N06AF06 Iproclozide

Active ingredients in N06AF

Active Ingredient Description
Iproniazide
Isocarboxazid

Isocarboxazid is a monoamine oxidase inhibitor, effective in small doses. Its antidepressant action is thought to be related to its effect on physiological amines such as serotonin and noradrenaline, and this effect is cumulative and persistent.

Phenelzine

Phenelzine is an irreversible non-selective inhibitor of monoamine oxidase. Although the exact mechanism of action has not been determined, it appears that the irreversible, nonselective inhibition of MAO by phenelzine relieves depressive symptoms by causing an increase in the levels of serotonin, norepinephrine, and dopamine in the neuron. Phenelzine is used for the treatment of major depressive disorder. Has also been used with some success in the management of bulimia nervosa.

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