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ATC Group: R03C Adrenergics for systemic use

Anatomical Therapeutic Chemical Classification System

Hierarchical position

Level
Code
Title
1
R
Respiratory system
2
R03
Drugs for obstructive airway diseases
3
R03C
Adrenergics for systemic use

Contents

Code
Title
R03CA
Alpha- and beta-adrenoreceptor agonists
R03CB
Non-selective beta-adrenoreceptor agonists
R03CC
Selective beta-2-adrenoreceptor agonists
R03CK
Adrenergics and other drugs for obstructive airway diseases

Active ingredients

Active Ingredient
Description
Bambuterol

Bambuterol is an active precursor of the selective β2-adrenergic agonist terbutaline. Bambuterol is the bis-N,N-dimethyl-carbamate of terbutaline. Bambuterol is a remarkably selective and potent inhibitor of cholinesterase. Bambuterol is indicated for the management of asthma, bronchospasm and/or reversible airways obstruction.

Clenbuterol

Clenbuterol is a direct-acting β2 sympathomimetic agent for the treatment of chronic obstructive airway diseases.

Ephedrine

Ephedrine is a sympathomimetic amine acting directly on the alpha and beta receptors and indirectly by increasing the release of noradrenaline by the sympathetic nerve endings. As with any sympathomimetic agent, ephedrine stimulates the central nervous system, the cardiovascular system, the respiratory system, and the sphincters of the digestive and urinary systems.

Hexoprenaline
Isoprenaline

Isoprenaline is a potent non selective beta-adrenergic agonist with low affinity for alphaadrenergic receptors. Isoprenaline acts primarily on the heart and on smooth muscle of bronchi, skeletal muscle vasculature and the gastrointestinal tract.

Metaproterenol

Orciprenaline sulphate is a bronchodilating agent. The bronchospasm associated with various pulmonary diseases-chronic bronchitis, pulmonary emphysema, bronchial asthma, silicosis, tuberculosis, sarcoidosis and carcinoma of the lung, has been successfully reversed by therapy with orciprenaline sulphate.

Salbutamol

Salbutamol is a selective β2-agonist providing short-acting (4-6 hour) bronchodilation with a fast onset (within 5 minutes) in reversible airways obstruction. At therapeutic doses it acts on the β2-adrenoceptors of bronchial muscle. Salbutamol is administered for the symptomatic relief of bronchospasm associated with chronic or acute asthma, bronchitis or other obstructive pulmonary diseases.

Terbutaline

Terbutaline sulfate is a selective beta2-adrenoceptor agonist, thus producing relaxation of bronchial smooth muscle, inhibition of the release of endogenous spasmogens, inhibitions of oedema caused by endogenous mediators, increased mucociliary clearance and relaxation of the uterine muscle.

Monographs

Monograph
Type
Country
BAMBEC Tablet
MPI, EU: SmPC
UK
BRICANYL Solution for injection or infusion
MPI, EU: SmPC
UK
EPHEDRINE HYDROCHLORIDE Solution for injection
MPI, EU: SmPC
UK