Chemical formula: C₁₀H₁₅NO Molecular mass: 165.232 g/mol PubChem compound: 9294
Ephedrine is a sympathomimetic amine acting directly on the alpha and beta receptors and indirectly by increasing the release of noradrenaline by the sympathetic nerve endings. As with any sympathomimetic agent, ephedrine stimulates the central nervous system, the cardiovascular system, the respiratory system, and the sphincters of the digestive and urinary systems.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01CA26 | Ephedrine | C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CA Adrenergic and dopaminergic agents |
| R01AA03 | Ephedrine | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AA Sympathomimetics, plain |
| R01AB05 | Ephedrine | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AB Sympathomimetics, combinations excl. corticosteroids |
| R03CA02 | Ephedrine | R Respiratory system → R03 Drugs for obstructive airway diseases → R03C Adrenergics for systemic use → R03CA Alpha- and beta-adrenoreceptor agonists |
| S01FB02 | Ephedrine | S Sensory organs → S01 Ophthalmologicals → S01F Mydriatics and cycloplegics → S01FB Sympathomimetics excl. antiglaucoma preparations |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| EPHEDRINE HYDROCHLORIDE Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| EPHEDRINE HYDROCHLORIDE Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| EPHEDRINE 1.0% Nasal drops | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Ephedrine is an active ingredient of these brands:
United States (US)Austria (AT)
Brazil (BR)
Cyprus (CY)
France (FR)
Hong Kong (HK)
Israel (IL)
Japan (JP)
Nigeria (NG)
Poland (PL)
Romania (RO)Singapore (SG)
South Africa (ZA)
Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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