Brand name authorized in: Italy
The drug ACESISTEM contains a combination of these active pharmaceutical ingredients (APIs):
Enalapril is a derivative of two amino-acids, L-alanine and L-proline. After absorption, enalapril is hydrolysed to enalaprilat, which inhibits ACE. Inhibition of ACE results in decreased plasma angiotensin II, which leads to increased plasma renin activity (due to removal of negative feedback of renin release), and decreased aldosterone secretion.
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows: