Enalapril

Also known as: Enalapril maleate

Active ingredient description

Enalapril is a derivative of two amino-acids, L-alanine and L-proline. After absorption, enalapril is hydrolysed to enalaprilat, which inhibits ACE. Inhibition of ACE results in decreased plasma angiotensin II, which leads to increased plasma renin activity (due to removal of negative feedback of renin release), and decreased aldosterone secretion.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Enalapril
C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain
Discover more medicines within C09AA02

Medicines

Enalapril is the active ingredient of these drugs:

Drug
Countries

Australia

Spain

Hong Kong Singapore

Brazil

Tunisia

Spain

Germany

Lithuania

Germany

Spain

Spain

Hong Kong Singapore

Austria

Lithuania

Brazil

Brazil

Hong Kong Ireland Lithuania Singapore

Brazil

Hong Kong Singapore Tunisia

Brazil

Lithuania

United States

Brazil

Brazil

Brazil Singapore

Spain

Spain

Ireland United Kingdom

Singapore

Cyprus

Cyprus Singapore

Hong Kong

Australia

Austria

Spain

Brazil

Brazil

Brazil

Brazil

Brazil

Brazil

Austria

Australia Austria Brazil France Netherlands

Brazil

Brazil

Hong Kong

Brazil

Canada United States

Canada

Germany

Enalapril is also found within below combination drugs:

ACEDIUR , ACETENSIL PLUS , ANGIOZIDE , BARIPRIL DIU , BAROPRINE , BENALAPRIL PLUS , CARMEN ACE , CENIPRES , CO-ENAC , CO-MEPRIL , CO-PRESSOTEC , CO-RENISTAD , CO-RENITEC , CORENITEC , CORIPREN , CORVO HCT , CRINORETIC , DABONAL PLUS , ELYRNO , ENABETA , ENAC PLUS HEXAL , ENACANPIN , ENAHEXAL COMP , ENALACOMP , ENALAGAMMA HCT , ENAP-H , ENAPLUS , ENEAS , ENIT , EUPRESSIN H , GLIOTENZIDE , HERTEN PLUS , HIPOARTEL PLUS , HYPRIL , INNOZIDE , LERCAPIN ACE , LERCAPREL , LERCAPRESS , LERCARIL , LERTEC , MALENA HCT , RENACOR , RENITEC PLUS , RENITECMAX , SINERGEN , VASERETIC , VASOPRIL PLUS , ZAN-EXTRA , ZANERIL , ZANEXTRA , ZANIPRESS , ZANIPRIL

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of product characteristics (SPC)
UK
Structured product labeling (SPL)
US

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

69PN84IO1A - ENALAPRIL

CAS registry number

75847-73-3 - enalapril

76095-16-4 - Enalapril maleate

SNOMED-CT

372658000 - Enalapril (substance)

414092003 - Product containing enalaprilat (medicinal product)