This brand name is authorized in Austria, Estonia, Croatia, Lithuania
The drug BUPENSAN DUO contains a combination of these active pharmaceutical ingredients (APIs):
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1
Buprenorphine
UNII 56W8MW3EN1 - BUPRENORPHINE HYDROCHLORIDE
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Buprenorphine is an opioid partial agonist/antagonist which attaches itself to the μ (mu) and κ (kappa) receptors of the brain. Its activity in opioid maintenance treatment is attributed to its slowly reversible link with the μ receptors which, over a prolonged period, minimises the need of illicit opioids for patients with opioid dependence. |
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2
Naloxone
UNII 5Q187997EE - NALOXONE HYDROCHLORIDE DIHYDRATE
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Naloxone hydrochloride, a semisynthetic morphine derivative (N-allyl-nor-oxymorphone), is a specific opioid antagonist that acts competitively at opioid receptors. It reveals very high affinity for the opioid receptor sites and therefore displaces both opioid agonists and partial antagonists, such as pentazocine, for example, but also nalorphine. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N07BC51 | Buprenorphine, combinations | N Nervous system → N07 Other nervous system drugs → N07B Drugs used in addictive disorders → N07BC Drugs used in opioid dependence |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1738368, 1738379, 1738380, 1738391, 1738997, 1739000, 1739011, 1739022, 1739033, 1739044, 1739055, 1739066 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1086260, 1086261, 1086262, 1086263, 1086264, 1086265, 1086266, 1086267, 1086268, 1086269, 1086270, 1086271, 1086272, 1086273, 1086274, 1086275, 1086276, 1086277, 1086278, 1086279, 1086280, 1086281, 1086282, 1086283 |
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