Buprenorphine

Also known as: Buprenorphine hydrochloride

Active ingredient description

Buprenorphine is an opioid partial agonist/antagonist which attaches itself to the μ (mu) and κ (kappa) receptors of the brain. Its activity in opioid maintenance treatment is attributed to its slowly reversible link with the μ receptors which, over a prolonged period, minimises the need of illicit opioids for patients with opioid dependence.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Buprenorphine
N Nervous system → N02 Analgesics → N02A Opioids → N02AE Oripavine derivatives
Discover more medicines within N02AE01
Buprenorphine
N Nervous system → N07 Other nervous system drugs → N07B Drugs used in addictive disorders → N07BC Drugs used in opioid dependence
Discover more medicines within N07BC01

Medicines

Buprenorphine is the active ingredient of these drugs:

Drug
Countries

Austria

United States

United Kingdom

United Kingdom

Austria Germany

United Kingdom

Germany

Australia

Germany

Germany

United States

Austria

Austria

Spain

United Kingdom

Canada Germany Ireland Netherlands Tunisia

Australia Austria Ireland Lithuania Spain

United Kingdom

Ireland United Kingdom

Spain

Spain

United Kingdom

United Kingdom

Brazil

Australia Austria Germany Hong Kong Lithuania

France

United Kingdom

United Kingdom

Canada

United Kingdom

Ireland United Kingdom

United Kingdom

Brazil

United Kingdom

Austria Ireland Lithuania United Kingdom

Singapore

Australia Canada United States

Australia Austria France Germany Ireland

Austria France Germany Hong Kong Ireland

Austria Brazil Germany Ireland Netherlands

Buprenorphine is also found within below combination drugs:

BUNALICT , BUNAVAIL , BUPENSAN DUO , SUBOXONE , ZUBSOLV

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of product characteristics (SPC)
Summary of product characteristics (SPC)
UK
Structured product labeling (SPL/PLR)
US
Structured product labeling (SPL/PLR)
US
Summary of product characteristics (SPC)
UK
Summary of product characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

40D3SCR4GZ - BUPRENORPHINE

CAS registry number

52485-79-7 - buprenorphine

53152-21-9 - Buprenorphine hydrochloride

SNOMED-CT

387173000 - Buprenorphine (substance)