Buprenorphine

Also known as: Buprenorphine hydrochloride

Brand names: ASTEC BELBUCA BUNAVAIL (in combination) BUPENSAN BUPENSAN DUO (in combination) BUPRENEX BUPRENOCAN BUPRETEC BUTRANS BUVIDAL NORSPAN PROBUPHINE SIXMO SOVENOR SUBLOCADE SUBOXONE (in combination) SUBUTEX TEMGESIC TRANSTEC ZUBSOLV (in combination)

Description

Buprenorphine is an opioid partial agonist/antagonist which attaches itself to the μ (mu) and κ (kappa) receptors of the brain. Its activity in opioid maintenance treatment is attributed to its slowly reversible link with the μ receptors which, over a prolonged period, minimises the need of illicit opioids for patients with opioid dependence.