KOVANAZE

This brand name is authorized in United States

Active ingredients

The drug KOVANAZE contains a combination of these active pharmaceutical ingredients (APIs):

1 Tetracaine
UNII 5NF5D4OPCI - TETRACAINE HYDROCHLORIDE

Tetracaine is a local anaesthetic and is believed to act by blocking nerve conduction mainly by inhibiting sodium ion flux across the axon membrane.

Read about Tetracaine
2 Oxymetazoline
UNII K89MJ0S5VY - OXYMETAZOLINE HYDROCHLORIDE

Oximetazoline is an imidazoline derivative. It exhibits sympathomimetic activity and specifically stimulates the α-adrenergic receptors of the sympathetic system. When administered topically to the nose it causes vasoconstriction of the expansed arterioles of the mucosal nose and a concurrent reduction in blood flow. It also reduces the hypersecretion of the nasal mucosa, ultimately contributing to the decongestion of the nasal mucosa.

Read about Oxymetazoline

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: US FDA, National Drug Code Identifier(s): 69803-100

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