Tetracaine Other names: Amethocaine Amethocaine hydrochloride Tetracaine Tetracaine hydrochloride

Chemical formula: C₁₅H₂₄N₂O₂  Molecular mass: 264.369 g/mol  PubChem compound: 5411

Active ingredient description

Tetracaine is a local anaesthetic and is believed to act by blocking nerve conduction mainly by inhibiting sodium ion flux across the axon membrane.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C05AD02 Tetracaine C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AD Local anesthetics
Discover more medicines within C05AD02
D04AB06 Tetracaine D Dermatologicals → D04 Antipruritics, incl. antihistamines, anesthetics, etc. → D04A Antipruritics, incl. antihistamines, anesthetics, etc. → D04AB Anesthetics for topical use
Discover more medicines within D04AB06
N01BA03 Tetracaine N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BA Esters of aminobenzoic acid
Discover more medicines within N01BA03
S01HA03 Tetracaine S Sensory organs → S01 Ophthalmologicals → S01H Local anesthetics → S01HA Local anesthetics
Discover more medicines within S01HA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MINIMS TETRACAINE HYDROCHLORIDE Single-use, sterile eye drops Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
AMETOP 4% w/w Gel Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 136-47-0
CAS Substance: 94-24-6
DrugBank Drug: DB09085
KEGG Drug: D00551
PubChem Compound: 5411
RxNorm Ingredient: 10391
SNOMED-CT Concept: 387309008
Tetracaine (substance)
UNII Identifier: 0619F35CGV
TETRACAINE

Medicines

Tetracaine is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Canada (CA)

  • AMETOP as TETRACAINE HYDROCHLORIDE

  • (combination) ONE TOUCH as TETRACAINE HYDROCHLORIDE
  • (combination) PLIAGLIS
  • (combination) ZAP as TETRACAINE HYDROCHLORIDE

Cyprus (CY)

  • (combination) DRILL as TETRACAINE HYDROCHLORIDE

France (FR)

  • SOLUTRICINE as TETRACAINE HYDROCHLORIDE

  • (combination) CANTALENE as TETRACAINE HYDROCHLORIDE
  • (combination) OTYLOL as TETRACAINE HYDROCHLORIDE

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • (combination) OTIDIN as TETRACAINE HYDROCHLORIDE

Japan (JP)

Mexico (MX)

  • PONTI as TETRACAINE HYDROCHLORIDE

Netherlands (NL)

New Zealand (NZ)

  • AMETOP as TETRACAINE HYDROCHLORIDE

  • (combination) TOPICAINE as TETRACAINE HYDROCHLORIDE
  • (combination) ZAP as TETRACAINE HYDROCHLORIDE

Poland (PL)

Romania (RO)

  • (combination) DRILL as TETRACAINE HYDROCHLORIDE

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

  • (combination) CANTALENE as TETRACAINE HYDROCHLORIDE

Turkey (TR)

United Kingdom (UK)

  • AMETOP as TETRACAINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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