NONAR

This brand name is authorized in Ecuador

Active ingredients

The drug NONAR contains a combination of these active pharmaceutical ingredients (APIs):

1 Guaifenesin
UNII 495W7451VQ - GUAIFENESIN

Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. In turn, this may increase the efficiency of the cough reflex and facilitate removal of the secretions. Guaifenesin is over-the-counter drug for the treatment of cough and common cold.

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2 Demorphan
UNII 9D2RTI9KYH - DEXTROMETHORPHAN HYDROBROMIDE

Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors.

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3 Phenylephrine
UNII 04JA59TNSJ - PHENYLEPHRINE HYDROCHLORIDE

Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
R01BA53 Phenylephrine, combinations R Respiratory system → R01 Nasal preparations → R01B Nasal decongestants for systemic use → R01BA Sympathomimetics
Discover more medicines within R01BA53

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: EC Agencia Nacional de Regulación, Control y Vigilancia Sanitaria Identifier(s): 7.865-1-04-03

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