Phenylephrine Other names: Neo-synephrine Phenylephrine hydrochloride
Chemical formula: C₉H₁₃NO₂ Molecular mass: 167.205 g/mol PubChem compound: 6041
Active ingredient description
Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| C01CA06 | Phenylephrine | C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CA Adrenergic and dopaminergic agents |
| C05AX06 | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AX Other agents for treatment of hemorrhoids and anal fissures for topical use | |
| R01AA04 | Phenylephrine | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AA Sympathomimetics, plain |
| R01AB01 | Phenylephrine | R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AB Sympathomimetics, combinations excl. corticosteroids |
| R01BA03 | Phenylephrine | R Respiratory system → R01 Nasal preparations → R01B Nasal decongestants for systemic use → R01BA Sympathomimetics |
| S01FB01 | Phenylephrine | S Sensory organs → S01 Ophthalmologicals → S01F Mydriatics and cycloplegics → S01FB Sympathomimetics excl. antiglaucoma preparations |
| S01GA05 | Phenylephrine | S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GA Sympathomimetics used as decongestants |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| PHENYLEPHRINE Injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| BOOTS BLOCKED NOSE RELIEF Capsules | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Phenylephrine is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)
Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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