PHOLEPHAMINE

This brand name is authorized in Hong Kong

Active ingredients

The drug PHOLEPHAMINE contains a combination of these active pharmaceutical ingredients (APIs):

1 Chlorphenamine
UNII V1Q0O9OJ9Z - CHLORPHENIRAMINE MALEATE

Chlorphenamine is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorphenamine also has anticholinergic activity.

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2 Guaifenesin
UNII 495W7451VQ - GUAIFENESIN

Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. In turn, this may increase the efficiency of the cough reflex and facilitate removal of the secretions. Guaifenesin is over-the-counter drug for the treatment of cough and common cold.

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3 Phenylephrine
UNII 04JA59TNSJ - PHENYLEPHRINE HYDROCHLORIDE

Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion.

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4 Pholcodine
UNII LPP64AWZ7L - PHOLCODINE

Pholcodine is an opioid that has been widely used for the treatment of non-productive cough in children and adults. Pholcodine is a cough suppressant with mild sedative but little analgesic activity. Additionally pholcodine is a marker for sensitization to neuromuscular blocking agents (NMBA) and is intended for use as a diagnostic tool in NMBA-induced anaphylaxis.

Read about Pholcodine

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: HK Department of Health Drug Office Identifier(s): 17890

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