Chemical formula: C₂₃H₃₀N₂O₄ Molecular mass: 398.495 g/mol PubChem compound: 5311356
Pholcodine is an opioid that has been widely used for the treatment of non-productive cough in children and adults. Pholcodine is a cough suppressant with mild sedative but little analgesic activity. Additionally pholcodine is a marker for sensitization to neuromuscular blocking agents (NMBA) and is intended for use as a diagnostic tool in NMBA-induced anaphylaxis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R05DA08 | Pholcodine | R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DA Opium alkaloids and derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| BOOTS DRY COUGH Syrup | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Pholcodine is an active ingredient of these brands:
France (FR)
Hong Kong (HK)
Ireland (IE)Lithuania (LT)
New Zealand (NZ)Singapore (SG)South Africa (ZA)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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