Chemical formula: C₂₃H₃₀N₂O₄ Molecular mass: 398.495 g/mol PubChem compound: 5311356
Pholcodine is a cough suppressant with mild sedative but little analgesic activity.
Maximum plasma concentrations are attained at 4 to 8 hours after an oral dose. The elimination half life ranges from 32 to 43 hours and volume of distribution is 30-49 l/kg.
Pholcodine is protein bound to the extent of 23.5%.
Pholcodine is metabolised in the liver but undergoes little conjugation.
There is little or no metabolism of pholcodine to morphine.
There are no preclinical data.
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