UNIFLU

This brand name is authorized in Malta

Active ingredients

The drug UNIFLU contains a combination of these active pharmaceutical ingredients (APIs):

1 Paracetamol
UNII 362O9ITL9D - ACETAMINOPHEN

Paracetamol is a medication used to treat pain and fever. It does appear to selectively inhibit COX activities in the brain, which may contribute to its ability to treat fever and pain.

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2 Phenylephrine
UNII 04JA59TNSJ - PHENYLEPHRINE HYDROCHLORIDE

Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion.

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3 Caffeine
UNII 3G6A5W338E - CAFFEINE

Caffeine is structurally related to the methylxanthines theophylline and theobromine. Caffeine’s main action is as a CNS stimulant.

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4 Diphenhydramine
UNII TC2D6JAD40 - DIPHENHYDRAMINE HYDROCHLORIDE

Diphenhydramine is an ethanolamine-derivative antihistamine. It is an antihistamine with anticholinergic and marked sedative effects. It acts by inhibiting the effects on H1-receptors. Diphenhydramine is effective in reducing sleep onset (i.e., time to fall asleep) and increasing the depth and quality of sleep.

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5 Codeine
UNII GSL05Y1MN6 - CODEINE PHOSPHATE

Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
R05X Other cold preparations R Respiratory system → R05 Cough and cold preparations
Discover more medicines within R05X

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: MT Medicines Authority Identifier(s): MA1333/00401

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