Codeine

Active ingredient description

Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Codeine
R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DA Opium alkaloids and derivatives
Discover more medicines within R05DA04

Medicines

Codeine is the active ingredient of these drugs:

Drug
Countries

Germany

Ireland

Spain

Germany

Germany

Germany

Singapore

Singapore

United Kingdom

Spain

Canada

France

Spain

France

Spain

Germany

Germany

Codeine is also found within below combination drugs:

ACETAZONE FORTE C8 , ACTCOFED , ACTIFED COMPOUND , AENDY , AGUD , ALGICOD , ALGIDOL , ALSEDYL , ANALGILASA , ANALGIPLUS , ANMEN , ANTARENE CODEINE , ANTICOL COUGH , ANTITUSS , ARACO , ARISTTO , ARSECOYL , ASCOMP WITH CODEINE , ASPALGIN , ASTEFOR , BAILIE , BEACODYL , BEACTAFED CO , BESCOFED , BIO-SED , BOLSEDYL , BROMCOLIN , BROMDINE , BROMESED , BROMETUSIN , BRONCODIN , BRONCOLIN , BRONKIN , BROSEDYL , CALMYLIN , CALMYLIN ACE , CALMYLIN PSE WITH CODEINE , CECOBOL , CECOL , CHLORSEDYL , CO-SEDYL , CO-TIPOL , CO-TUSIN , CO-TUSIU , COBELIN , COBO , COCLEAN , COCURE , COD-EFFERALGAN , CODALGIN FORTE , CODAPANE FORTE , CODASOLVE , CODATEN , CODEX , CODEY , CODINEX , CODIPAR , CODIS , CODIXINE , CODOLAX , CODOLAX COMPLEX , CODOLIPRANE , CODOPLEX , COFEDPO , COFETOL , COFFTIER , COFLUKON , COL-LERGIC , COLASED , COLESS COUGH , COLSEDYL , COMEPHEN , COMETIN , COMFAROL FORTE , CONDOSA , COPALIN , COPAMINE , COPHADYL , COPHADYL-E , COPHENSIN , CORIN , CORME , CORY , COSEDIN , COSEDYL , COSO , COSOTAL , COTALIN , COTIN , COUGHLAX , CROSEDYL , CUPATUSSIN , DAFALGAN CODEINE , DAMYLIN WITH CODEINE , DECOFFA , DECOL , DEWEAR COUGH , DEXCOFED , DIMECO , DIMETAPP-C , DIPHECO , DIPHETAN , DOLMEN , DOLOCATIL CODEINA , DOLODENS , DOLOMEDIL , DOLVIRAN , DULSANA WITH CODEINE , ECOMET , ECOSIN , EDENA , EENDEL LIGHT , EFENDEL , EIONE COUGH , EMCOZIN , EPHCOUGH , EPHECO , EPHENDYLN , EUPHON , EUROSEDYL , FAMISEDYL , FEDAC COMPOUND , FENCO COUGH , FENCODYL , FENCOLIN COUGH , FENDIL , FENDYL , FERRALI , FESCOFED , FIORICET WITH CODEINE , FIORINAL WITH CODEINE , FIORINAL-C , FLUDETEN , FOLSEDYL , FRICOLIN , FUSTALIM , GECOL , GELONIDA , GOBY COUGH , GROSEDYL , HOLSEDYL , IBUCOD , IMMENSAE , JENDEL , JENDYL , KAPAKE , KENDEL , KLIPAL CODEINE , KOLSEDYL , KONTUSSIN , KROSEDYL , LAMBAR , LAVENDA , LECOL , LINDILANE , LOLSEDYL , LONARID-N , MAXILIEF , MECODIN , MEGATUSSIC , MEPHENDYL , MERSIDYL , MERSYNDOL WITH CODEINE , MESADIN , METASIN , METHARINE , MIGRALEVE , MIGRALEVE PINK , MIGRALEVE YELLOW , MONIC COUGH , MROSEDYL , MYCODIN , NASEDYL , NAVOSE , NEOBRUFEN CON CODEINA , NEODINE , NOLSEDYL , NORVICOL , NUROFEN PLUS , OPTIPYRIN , OROSEDYL , PACO , PACOFEN , PAFFEICO , PANACO , PANADEINE , PANADOL ULTRA , PANAMAX-CO , PARACODOL , PARCOTEN , PECOLIN , PHECOBO , PHECOMIN-N , PHENAZOL , PHENCOUGH , PHENEXPECT CD , PHENSEDYN , PHENTAGON , PHENZINCO , POCODYL , POLESEDYL , POSODIN , PRESEDYL , PRO-COTIN , PRO-PHECO , PROCODIN , PROCODINE , PROCOSED , PROCOTUSS , PRODEINE FORTE , PROMEDYL-B , PROMELIX , PRONTALGINE , PROPHENIN ELIXIR , PROSEDIN , PROSEDINE , PROSEDYL , PROSODIN , QUENCOL , ROBAXACET-8 , ROBAXISAL C , RROSEDYL , SECOLIN-F , SEDYLIN , SENDY , SOLPADEINE , SOLPADEINE MIGRAINE , SOLPADOL , SOLSEDYL COUGH , SUNSEDYL , SUPHENIN , SURSEDYL , SURTUSSIN , SYNDOL HEADACHE RELIEF , TALVOSILEN , TERMALDINA , TITRETTA , TOLSEDYL , TOUSEDYL , TRIATEC-30 , TRICOS COUGH , TROSEDYL , TUCOSOL , TUCOUSOL , TUSINCO , TUSSIPAX , TUSSORAL , TUXARIN , TUZISTRA XR , TYLENOL WITH CODEINE , TYLEX , U-CODOBEX , U-PHENCO , ULTRACOD , ULTRAMOL , UNI-CODPLEX , UNI-COLIN , UNI-FEDRA COMPOUND , UNIDRYL CD , UNIFLU WITH GREGOVITE C , UNISEDYL FORTE , VANDAFU , VEGANIN , VICKOLAX , VICODIL , VOLSEDYL COUGH , WINSEDYL , XOLSEDYL , ZAPAIN , ZECOL COUGH , ZOLLAR

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of product characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

GSL05Y1MN6 - CODEINE PHOSPHATE

Q830PW7520 - CODEINE

CAS registry number

41444-62-6 - Codeine phosphate

52-28-8 - Codeine phosphate hemihydrate

SNOMED-CT

387494007 - Codeine (substance)