NUROFEN PLUS

This brand name is authorized in Ireland, Israel, Malta, New Zealand, Poland, Romania, Turkey, United Kingdom, South Africa

Active ingredients

The drug NUROFEN PLUS contains a combination of these active pharmaceutical ingredients (APIs):

1 Ibuprofen
UNII WK2XYI10QM - IBUPROFEN

Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation.

Read about Ibuprofen
2 Codeine
UNII GSL05Y1MN6 - CODEINE PHOSPHATE

Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain.

Read about Codeine

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
NUROFEN PLUS Film-coated tablet Health Products Regulatory Authority (IE) MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
M01AE51 Ibuprofen, combinations M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives
Discover more medicines within M01AE51

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 100581, 39157
Country: IL מִשְׂרַד הַבְּרִיאוּת Identifier(s): 5147
Country: MT Medicines Authority Identifier(s): MA1447/00101, MA1447/00105
Country: NZ Medicines and Medical Devices Safety Authority Identifier(s): 11463
Country: PL Rejestru Produktów Leczniczych Identifier(s): 100200049
Country: RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale Identifier(s): W66071001, W66071002, W66071005, W66071006
Country: TR İlaç ve Tıbbi Cihaz Kurumu Identifier(s): 8690570090017
Country: ZA Health Products Regulatory Authority Identifier(s): 37/2.7/0666

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