ATC Group: M01AE Propionic acid derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of M01AE in the ATC hierarchy

Level Code Title
1 M Musculo-skeletal system
2 M01 Antiinflammatory and antirheumatic products
3 M01A Antiinflammatory and antirheumatic products, non-steroids
4 M01AE Propionic acid derivatives

Group M01AE contents

Code Title
M01AE01 Ibuprofen
M01AE02 Naproxen
M01AE03 Ketoprofen
M01AE04 Fenoprofen
M01AE05 Fenbufen
M01AE06 Benoxaprofen
M01AE07 Suprofen
M01AE08 Pirprofen
M01AE09 Flurbiprofen
M01AE10 Indoprofen
M01AE11 Tiaprofenic acid
M01AE12 Oxaprozin
M01AE13 Ibuproxam
M01AE14 Dexibuprofen
M01AE15 Flunoxaprofen
M01AE16 Alminoprofen
M01AE17 Dexketoprofen
M01AE18 Naproxcinod
M01AE51 Ibuprofen, combinations
M01AE52 Naproxen and esomeprazole
M01AE53 Ketoprofen, combinations
M01AE56 Naproxen and misoprostol
M01AE57

Active ingredients in M01AE

Active Ingredient Description
Dexibuprofen

Dexibuprofen is considered to be the pharmacologically active enantiomer of racemic ibuprofen. Racemic ibuprofen is a non-steroidal substance with antiinflammatory and analgesic effects. Its mechanism of action is thought to be due to inhibition of prostaglandin synthesis.

Dexketoprofen

Dexketoprofen belongs to the non-steroidal anti-inflammatory group of drugs. The mechanism of action of Dexketoprofen is related to the reduction of prostaglandin synthesis by the inhibition of cyclooxygenase pathway. Furthermore, the inhibition of the synthesis of prostaglandins could affect other inflammation mediators such as kinins, causing an indirect action which would be additional to the direct action.

Fenoprofen

Fernoprofen has analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of prostaglandin synthesis. Its mode of action may be due to a decrease of prostaglandins in peripheral tissues.

Flurbiprofen

Flurbiprofen is a propionic acid derivative NSAID which acts through inhibition of prostaglandin synthesis. In humans flurbiprofen has potent analgesic, antipyretic and anti-inflammatory properties.

Ibuprofen

Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation.

Ketoprofen

Ketoprofen is a non-steroidal anti-inflammatory drug. It has anti-inflammatory and analgesic actions.

Naproxen

Naproxen is a non-steroidal anti-inflammatory analgesic compound with antipyretic properties as has been demonstrated in classical animal test systems. Naproxen exhibits its anti-inflammatory effect even in adrenalectomised animals, indicating that its action is not mediated through the pituitary-adrenal axis.

Oxaprozin

Oxaprozin has analgesic, anti-inflammatory, and antipyretic properties. The mechanism of action of oxaprozin, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2).

Suprofen
Tiaprofenic acid

Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, especially arthritic pain. Results of in-vitro experiments and ex-vivo studies suggest a neutral or possibly beneficial effect of tiaprofenic acid on joint cartilage under experimental conditions.

Zaltoprofen

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