Ibuprofen
Chemical formula: C₁₃H₁₈O₂ Molecular mass: 206.281 g/mol PubChem compound: 3672
Active ingredient description
Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| C01EB16 | Ibuprofen | C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EB Other cardiac preparations |
| G02CC01 | Ibuprofen | G Genito urinary system and sex hormones → G02 Other gynecologicals → G02C Other gynecologicals → G02CC Antiinflammatory products for vaginal administration |
| M01AE01 | Ibuprofen | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives |
| M02AA13 | Ibuprofen | M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AA Antiinflammatory preparations, non-steroids for topical use |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| TEFIN Suppository | MPI, EU: SmPC | Health Products Regulatory Authority (IE) | |
| BRUFEN 400 mg Tablet | MPI, EU: SmPC | Health Products Regulatory Authority (IE) | |
| IBUPROFEN 400mg Film-coated tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| IBU Tablet | MPI, US: SPL/Old | FDA, National Drug Code (US) | |
| IBUPROFEN 600mg Film-coated tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| CALPROFEN Oral suspension | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| NUROFEN DURANCE Medicated plaster | MPI, EU: SmPC | Health Products Regulatory Authority (IE) | |
| FENBID 10% w/w Gel | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| PEDEA Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) |
Medicines
Ibuprofen is an active ingredient of these brands:
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