Ibuprofen

Active ingredient description

Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Ibuprofen
C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EB Other cardiac preparations
Discover more medicines within C01EB16
Ibuprofen
G Genito urinary system and sex hormones → G02 Other gynecologicals → G02C Other gynecologicals → G02CC Antiinflammatory products for vaginal administration
Discover more medicines within G02CC01
Ibuprofen
M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives
Discover more medicines within M01AE01
Ibuprofen
M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AA Antiinflammatory preparations, non-steroids for topical use
Discover more medicines within M02AA13

Medicines

Ibuprofen is the active ingredient of these drugs:

Drug
Countries

Lithuania

Ireland

South Africa

Austria

Brazil Canada France Hong Kong Netherlands

Austria Germany

Spain

Spain

Cyprus

Italy

Cyprus

Brazil

Spain

Brazil

Hong Kong

United Kingdom

United Kingdom

United Kingdom

France

Spain

Spain

Spain

Brazil

South Africa

Poland

Spain

Poland

Tunisia

South Africa

South Africa

Hong Kong Singapore

Singapore

South Africa

Australia Austria Cyprus France Hong Kong

Lithuania

Hong Kong

Ireland

Hong Kong

Ireland

Hong Kong

Brazil

Finland

Brazil Cyprus Poland

Lithuania

Poland

United States

United Kingdom

Brazil

Hong Kong

United Kingdom

Tunisia

Brazil Spain

Lithuania

Spain

Austria Germany

Tunisia

Spain

Austria Germany Lithuania Poland Tunisia

Hong Kong

Germany

Austria

Spain

Germany

Tunisia

Brazil

South Africa

Ireland

Hong Kong

Spain

Spain

Germany

Hong Kong

Spain

Hong Kong

United Kingdom

South Africa United Kingdom

Ireland

New Zealand United Kingdom

United Kingdom

Spain

Tunisia

Hong Kong

New Zealand

Austria

Poland

Poland

South Africa

Hong Kong

IBU

United States

Spain United Kingdom

South Africa Tunisia

South Africa

Germany

Spain

Germany Lithuania Poland

Lithuania

Spain

Hong Kong Lithuania Poland Singapore Spain

France

Germany

Brazil

Brazil

Lithuania

Ireland United Kingdom

New Zealand South Africa

Germany

Spain

Spain

United Kingdom

South Africa United Kingdom

Brazil

Poland

Italy

Finland Lithuania Poland

South Africa

Austria Finland Lithuania

South Africa

Poland

Austria

Poland

Tunisia

France

Tunisia

Poland

Brazil

Lithuania Poland

Poland

Poland

Hong Kong

Finland

Germany Spain

South Africa

Hong Kong

United Kingdom

Lithuania

Spain

Finland

Poland

Germany

Germany Lithuania

Finland

Lithuania

Brazil

Poland

Finland

Hong Kong

Hong Kong

South Africa

Hong Kong

Hong Kong

Hong Kong

Spain

Hong Kong

Poland

Hong Kong

South Africa

Spain

Poland

Lithuania

South Africa

Tunisia

Brazil

Ireland

Poland

Ireland

Tunisia

Brazil Canada United States

Austria Spain Tunisia

United States

Germany

Hong Kong

South Africa

Spain

Spain

Tunisia

Brazil

Spain

Canada

Austria France

South Africa

Austria Cyprus France Germany Hong Kong

Lithuania

Brazil

Spain

Tunisia

Singapore

Austria Finland France Hong Kong Ireland

Germany

Cyprus Hong Kong Singapore

Germany

Ireland United Kingdom

Spain

Spain

Hong Kong

Cyprus

Cyprus Hong Kong

Hong Kong

Spain

Germany

France Hong Kong Poland Singapore

Italy Netherlands

France

Hong Kong

Brazil

Austria

Germany

Hong Kong

Lithuania

France Tunisia

Brazil

Hong Kong

Tunisia

Hong Kong Singapore

Ibuprofen is also found within below combination drugs:

ADOBIL , ADVIL COLD & FLU , ADVIL COLD & SINUS CONVENIENCE PACK , ADVIL COLD & SINUS LIQUI-GELS , ADVIL COLD & SINUS PLUS , ADVIL COLD AND SINUS , ADVIL COLD AND SINUS DAYTIME , ADVIL COLD AND SINUS NIGHTTIME , ADVIL COLD, COUGH & FLU NIGHTTIME , ADVIL COLD, SINUS & FLU EXTRA STRENGTH , ADVIL DAY/NIGHT CONVENIENCE PACK , ADVIL NIGHTTIME , ADVIL ZATOKI , ANTARENE CODEINE , APAP INTENSE , APSELAN PLUS , ARDINEX , ASTEFOR , BI-GESIC , BISOLFREN , BOXAGRIPPAL , BRUPRO COLD & FLU , BURANA-C , BYFONEN PLUS , CLIPTOL , COMBOGESIC , DAIKOL , DEMAZIN COLD AND FLU , DENTOPAIN , DENTOPAIN FORTE , DIP RILIF , DOLERIN , DOLORFLU , DOLOSTOP PLUS , DOLVEN RHUME , DUEXIS , DUOMAX , DUORIN , EASOLIEF DUO , FLUSTAD , GEN-PAYNE , GRIPADUO , IBALGIN SPORT , IBU-SPA , IBUCOD , IBUCODE PLUS , IBUCOMP , IBUFIX , IBUM GRIP , IBUM ZATOKI , IBUMAX COLD & FLU , IBUMAX-C , IBUMENT , IBUMOL , IBUMOL FORTE , IBUPAIN , IBUPAIN FORTE , IBURHUME , IBUSIN , ILOXEN , INFEX , IPRAFEINE , KIDOFEN DUO , LOTEM , LUFTAFEM , MAXIGESIC , MAXIGESIC PE , MEDIX SINUS PE , METAFEN , METAFENEX , MODAFEN EXTRA GRIP , MODAFEN GRIP , MOTRIN PLATINUM , MUCOCOLD , MYBUCOD , MYBULEN , MYPAID , MYPRODOL , NEOBRUFEN CON CODEINA , NUROFEN COLD & FLU PE , NUROFEN COLD AND FLU , NUROFEN COLD AND FLU RELIEF , NUROFEN DAY AND NIGHT , NUROFEN PLUS , NUROFEN RHUME , NUROFEN SINUS AND PAIN , NUROFEN ULTIMA , NUROFEN ZATOKI , NUROMOL , PHARMAFREN , RHINADVIL RHUME , ROBAX PLATINUM , SALVARINA , SOLPADEINE MIGRAINE , SPIDUFEN , SUDAFED SINUS PAIN RELIEF , SUDAFED SINUS PRESSURE & PAIN , THOMADUO , TUOAN , WICK DAYMED DUO , ZATOTABS

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Structured Product Monograph (SPM)
CA

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

WK2XYI10QM - IBUPROFEN

CAS registry number

15687-27-1 - Ibuprofen

SNOMED-CT

387207008 - Ibuprofen (substance)