Ibuprofen

Active ingredient description

Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Ibuprofen
C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EB Other cardiac preparations
Discover more medicines within C01EB16
Ibuprofen
G Genito urinary system and sex hormones → G02 Other gynecologicals → G02C Other gynecologicals → G02CC Antiinflammatory products for vaginal administration
Discover more medicines within G02CC01
Ibuprofen
M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives
Discover more medicines within M01AE01
Ibuprofen
M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AA Antiinflammatory preparations, non-steroids for topical use
Discover more medicines within M02AA13

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Structured Product Monograph (SPM)
CA
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK

Medicines

Ibuprofen is the active ingredient of these drugs:

Drug
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Ibuprofen is also found within below combination drugs:

ADOBIL , ADVIL COLD & FLU , ADVIL COLD & SINUS CONVENIENCE PACK , ADVIL COLD & SINUS LIQUI-GELS , ADVIL COLD & SINUS PLUS , ADVIL COLD AND SINUS , ADVIL COLD AND SINUS DAYTIME , ADVIL COLD AND SINUS NIGHTTIME , ADVIL COLD, COUGH & FLU NIGHTTIME , ADVIL COLD, SINUS & FLU EXTRA STRENGTH , ADVIL DAY/NIGHT CONVENIENCE PACK , ADVIL NIGHTTIME , ADVIL ZATOKI , ALGITRIN , ANALGEX , ANALGION FEM , ANTARENE CODEINE , APAP INTENSE , APIREKS C , APIREKS COLD & FLU , APSELAN PLUS , ARDINEX , ASTEFOR , BERALFENO , BI-GESIC , BIOFEN EXTRA , BISOLFREN , BOXAGRIPPAL , BRUFEN COLD & FLU , BRUFEN PLUS , BRUPRO COLD & FLU , BUPREX FEM , BUPREX FLEX , BUPREX MIGRA , BUPREX RELAX , BURANA-C , BUSCAPINA FEM , BYFONEN PLUS , CAFIBEXX , CETAFLUX AC , CLIPTOL , COLDAWAY C , COLDAWAY COLD & FLU , COLDAWAY PLUS , COLDFEN , COLDFEN ZERO , COMBIFEXIN , COMBOGESIC , DAIKOL , DEEP RELIEF , DEMAZIN COLD AND FLU , DENTOPAIN , DENTOPAIN FORTE , DIP RILIF , DOLERIN , DOLFEMIN DUAL , DOLORFLU , DOLORGESIC RELAX , DOLORIN COLD , DOLORPAN FORTE , DOLOSTOP PLUS , DOLVEN COLD & FLU , DOLVEN RHUME , DOVIR , DROFLU COLD , DROFLU COLD PLUS , DUEXIS , DUOMAX , DUOPAS , DUORIN , EASOLIEF DUO , ECE , EFFICOL PLUS , ELOMEN , FEBERTT MIGRA , FEBRILEK , FEMMEXTRA , FINALIN FEM , FLUKIT PLUS , FLUSTAD , FLUTURAN , FORFLU , GEN-PAYNE , GRIBEX COLD & FLU , GRIBO COLD , GRIPADUO , IBALGIN DUO , IBALGIN SPORT , IBIZOL , IBU-SPA , IBUCOD , IBUCODE PLUS , IBUCOLD , IBUCOLD C , IBUCOMP , IBUDOL MIGRAX , IBUFIX , IBUFLASH MIGRAN , IBUGRIP PLUS , IBUM GRIP , IBUM ZATOKI , IBUMAX COLD & FLU , IBUMAX-C , IBUMEDICA , IBUMENT , IBUMOL , IBUMOL FORTE , IBUPAIN , IBUPAIN FORTE , IBUPAR FORTE , IBUPAXX , IBURAMIN COLD , IBURAMIN ZERO , IBURHUME , IBUSIN , IBUSINUS , IBUSTOP , IBUVALEN DUO , IBUVALEN FLU , IBUXX MIGRA , ILOXEN , INFEX , INFLANOR PLUS , IPRAFEINE , KIDOFEN DUO , LAROFEN PLUS , LOTEM , LUFTAFEM , MAXIGESIC , MAXIGESIC PE , MEDIX SINUS PE , METAFEN , METAFENEX , MIGRAFEINA-ER , MIGRAFLASH , MIGRALFEN , MIGRAMIL , MIGRASTOP , MINIDRIN COLD , MODAFEN , MODAFEN EXTRA GRIP , MODAFEN GRIP , MOLAR-EX , MOTRIN PLATINUM , MOVIPREN , MUCOCOLD , MULTIDOL ULTRA , MYBUCOD , MYBULEN , MYORIL , MYPAID , MYPRODOL , NEOBRUFEN CON CODEINA , NEOFED COLD & FLU , NIMPAS , NORAVER G , NORAVER G FAST , NORMOTEMP ODO , NUROFEN COLD & FLU PE , NUROFEN COLD AND FLU , NUROFEN COLD AND FLU RELIEF , NUROFEN DAY AND NIGHT , NUROFEN PLUS , NUROFEN RHUME , NUROFEN SINUS AND PAIN , NUROFEN ULTIMA , NUROFEN ZATOKI , NUROMOL , OROFEN COLD & FLU , PADUDEN DUO , PANADO PLUS , PARACOLIC , PARAFENGEN , PARALGEN PLUS , PASSIF FORTE , PEDIFEN COLD & FLU , PENCOLD , PHARMAFREN , PROFINAL MIGRA , PROFINAL RELAX , RHINADVIL RHUME , ROBAX GOLD , ROBAX PLATINUM , RUFEN FORTE , SALVARINA , SOLPADEINE MIGRAINE , SPIDUFEN , SUDAFED SINUS PAIN RELIEF , SUDAFED SINUS PRESSURE & PAIN , SYNOCAM , TASIFEN MIGRANA , TASIFEN MUSCULAR , TEDOLFEN , TENSORELAX FORTE , TENSOVID PLUS , TENVALIN FLU , TERMO DOLOGRIP , THOMADUO , TIOCOLFEN , TIORELAX , TONUFEN , TUOAN , USPAFEN SINUS , WICK DAYMED DUO , ZATOTABS

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₃H₁₈O₂
Molecular mass: 206.281 g/mol

External identifiers

CAS Substance: 15687-27-1
DrugBank Drug: DB01050
KEGG Drug: D00126
PubChem Compound: 3672
RxNorm Ingredient: 5640
SNOMED-CT Concept: 387207008
Ibuprofen (substance)
UNII Identifier: WK2XYI10QM
IBUPROFEN