Ibuprofen

Chemical formula: C₁₃H₁₈O₂  Molecular mass: 206.281 g/mol  PubChem compound: 3672

Active ingredient description

Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01EB16 Ibuprofen C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EB Other cardiac preparations
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G02CC01 Ibuprofen G Genito urinary system and sex hormones → G02 Other gynecologicals → G02C Other gynecologicals → G02CC Antiinflammatory products for vaginal administration
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M01AE01 Ibuprofen M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives
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M02AA13 Ibuprofen M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AA Antiinflammatory preparations, non-steroids for topical use
Discover more medicines within M02AA13

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
IBUPROFEN 600mg Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
FENBID 10% w/w Gel Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
IBUPROFEN 400mg Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CALPROFEN Oral suspension Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MOTRIN Tablet Health Products and Food Branch (CA) MPI, CA: SPM

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 15687-27-1
DrugBank Drug: DB01050
KEGG Drug: D00126
PubChem Compound: 3672
RxNorm Ingredient: 5640
SNOMED-CT Concept: 387207008
Ibuprofen (substance)
UNII Identifier: WK2XYI10QM
IBUPROFEN

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