Nurofen Plus Tablets Ibuprofen 200mg Codeine Phosphate Hemihydrate 12.8mg.
| Pharmaceutical Form |
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Film-coated Tablet (Tablet). Nurofen Plus is a white film-coated, biconvex capsule-shaped tablet embossed with the logo ‘N+’ on one side. |
Each tablet contains Ibuprofen 200.0 mg and Codeine Phosphate Hemihydrate 12.8 mg.
For a full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Codeine |
Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
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| Ibuprofen |
Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation. |
| List of Excipients |
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Tablet core |
Blister packs (250 micron PVC/40gsm PVDC heat sealed to aluminium foil) containing 6, 12 or 24 tablets (OTC pack sizes).
Blister packs (250 micron PVC/40gsm PVDC heat sealed to aluminum foil) containing 32 or 48 tablets (POM pack sizes).
Not all pack sizes may be marketed.
Reckitt Benckiser Ireland Ltd, 7 Riverwalk, Citywest Business Campus, Dublin 24, Ireland
PA0979/034/001
Date of first authorisation: 21 March 1997
Date of last renewal: 21 March 2007
| Drug | Countries | |
|---|---|---|
| NUROFEN PLUS | Ireland, Israel, Malta, New Zealand, Poland, Romania, Turkey, United Kingdom, South Africa |
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