SIMECO

This brand name is authorized in Brazil, Turkey

Active ingredients

The drug SIMECO contains a combination of these active pharmaceutical ingredients (APIs):

1 co-dried Aluminium hydroxide and Magnesium carbonate
UNII RFJ7QXF345 - ALUMINUM MAGNESIUM HYDROXIDE CARBONATE

Aluminium hydroxide is a slow-acting antacid. It is used to provide symptomatic relief in gastric hyperacidity. In addition, the antipeptic and demulcent activity of aluminium hydroxide helps to protect inflamed gastric mucosa against further irritation by gastric secretions.

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2 Magnesium hydroxide
UNII NBZ3QY004S - MAGNESIUM HYDROXIDE

Magnesium hydroxide is practically insoluble in water and solution is not effected until the hydroxide reacts with hydrochloric acid in the stomach to form magnesium chloride. Its neutralising action is almost equal to that of sodium bicarbonate. When the dose is in excess of that required to neutralise the acid the intragastric pH may reach pH 8 or 9. Acid rebound following magnesium hydroxide is clinically insignificant. Magnesium hydroxide has an indirect cathartic effect resulting from water retention in the intestinal lumen.

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3 Simethicone
UNII 92RU3N3Y1O - DIMETHICONE

Simethicone is a chemically inert, non-systemic gastric defoaming agent that works by altering the elasticity of interfaces of mucus-embedded bubbles in the gastrointestinal tract. The gas bubbles are thus broken down or coalesced and in this form gas is more easily eliminated through eructation or passing flatus.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
A02AF Antacids with antiflatulents A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02A Antacids
Discover more medicines within A02AF
A02AF02 Ordinary salt combinations and antiflatulents A Alimentary tract and metabolism → A02 Drugs for acid related disorders → A02A Antacids → A02AF Antacids with antiflatulents
Discover more medicines within A02AF02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: BR Câmara de Regulação do Mercado de Medicamentos Identifier(s): 508011802135411, 508011804138416
Country: TR İlaç ve Tıbbi Cihaz Kurumu Identifier(s): 8699519700116

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