ICD-10 Specific code C37: Malignant neoplasm of thymus
Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.
Translations
| Language | Translation |
|---|---|
English
|
Malignant neoplasm of thymus |
French
|
Tumeur maligne du thymus |
Hierarchical position
| Level | Code | Title | |
|---|---|---|---|
| 1 | II | Neoplasms | |
| 2 | C00-C97 | Malignant neoplasms | |
| 3 | C30-C39 | Malignant neoplasms of respiratory and intrathoracic organs | |
| 4 | C37 | Malignant neoplasm of thymus |
Indicated medicines
| Active Ingredient |
|---|
|
Ifosfamide is an antineoplastic, a cytotoxic alkylating agent. It is a prodrug and shows no in vitro cytotoxic activity until activated by microsomal enzymes. The cytotoxic activity of ifosfamide (alkylation of the nucleophilic centres in the cells) is associated with the activated oxazaphosphorine ring hydroxylated at the C4 atom which interacts with DNA-DNA cross linking. This activity manifests itself by blocking the late S and early G2 phases of the cell cycle. |
|
Melphalan is a bifunctional alkylating agent. Formation of carbonium intermediates from each of the two bis-2-chloroethyl groups enables alkylation through covalent binding with the 7-nitrogen of guanine on DNA, cross-linking the two DNA strands and thereby preventing cell replication. |