Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.
| Language | Translation |
|---|---|
English
|
Juvenile polyarthritis (seronegative) |
French
|
Polyarthrite juvénile (séronégative) |
| Level | Code | Title | |
|---|---|---|---|
| 1 | XIII | Diseases of the musculoskeletal system and connective tissue | |
| 2 | M05-M14 | Inflammatory polyarthropathies | |
| 3 | M08 | Juvenile arthritis | |
| 4 | M08.3 | Juvenile polyarthritis (seronegative) |
| Active Ingredient | Description | |
|---|---|---|
| Tocilizumab |
Tocilizumab binds specifically to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R). IL-6 is involved in diverse physiological processes such as T-cell activation, induction of immunoglobulin secretion, induction of hepatic acute phase protein synthesis and stimulation of haemopoiesis. IL-6 has been implicated in the pathogenesis of diseases including inflammatory diseases, osteoporosis and neoplasia. |
