Pruritus

Active Ingredient: Hydroxyzine

Indication for Hydroxyzine

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)
Therapeutic intent: Curative procedure

Hydroxyzine is indicated in the symptomatic treatment of pruritus in adults, adolescents and children from 12 months of age.

For this indication, competent medicine agencies globally authorize below treatments:

25 mg once as starting dose followed with doses up to 25 mg 3 to 4 times daily

For:

Dosage regimens

Oral, 25 milligrams hydroxyzine, at the end of the day, one dose. Afterwards, oral, 25 milligrams hydroxyzine, 3 to 4 times daily. The maximum allowed total dose is 100 milligrams hydroxyzine daily.

Detailed description

Hydroxyzine should be used at the lowest effective dose and for the shortest possible duration.

For symptomatic treatment of pruritus in adults, 18 years of age:

Starting dose of 25 mg up to 1 hour before going to bed, to be followed if necessary with doses up to 25 mg 3 to 4 times daily.

In adults, the maximum daily dose is 100 mg per day.

12.5 mg as starting dose followed by a maximum daily dose of 50 mg in 3-4 divided doses

For:

Dosage regimens

Oral, 12.5 milligrams hydroxyzine, at the end of the day, one dose, over the duration of 1 day. Afterwards, oral, 50 milligrams hydroxyzine, divided 3 to 4 times daily. The maximum allowed total dose is 50 milligrams hydroxyzine daily.

Detailed description

Hydroxyzine should be used at the lowest effective dose and for the shortest possible duration.

Starting dose of 25 mg up to 1 hour before going to bed, to be followed if necessary with doses up to 25 mg 3 to 4 times daily.

In elderly patients it is recommended to initiate treatment with half the recommended dose due to prolonged effect. The lowest possible dose should be chosen when treating the elderly. The maximum daily dose for the elderly is 50 mg/day.

1-2 mg/kg/day in divided doses

For:

Dosage regimens

Oral, between 1 milligrams hydroxyzine per kilogram of body weight and 2 milligrams hydroxyzine per kilogram of body weight, divided daily, 3 doses in total.

Detailed description

In children from 12 months: 1 mg/kg/day up to 2 mg/kg/day in divided doses.

In children up to 40 kg in weight, the maximum daily dose is 2 mg/kg/day. In children over 40 kg in weight, the maximum daily dose is 100 mg/day.

Active ingredient

Hydroxyzine

Hydroxyzine is a psycholeptic and anxiolytic agent (ataractic). Hydroxyzine dihydrochloride is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the central nervous system.

Read more about Hydroxyzine

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