Hydroxyzine

Chemical formula: C₂₁H₂₇ClN₂O₂  Molecular mass: 374.904 g/mol  PubChem compound: 3658

Active ingredient description

Hydroxyzine is a first generation antihistamine, a piperazine derivative, with antimuscarinic and sedative properties.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N05BB01 Hydroxyzine N Nervous system → N05 Psycholeptics → N05B Anxiolytics → N05BB Diphenylmethane derivatives
Discover more medicines within N05BB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ATARAX Film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 1244-76-4
CAS Substance: 68-88-2
DrugBank Drug: DB00557
KEGG Drug: D08054
PubChem Compound: 3658
RxNorm Ingredient: 5553
SNOMED-CT Concept: 372856003
Hydroxyzine (substance)
UNII Identifier: 30S50YM8OG
HYDROXYZINE

Medicines

Hydroxyzine is an active ingredient of these brands:

United States (US)

Austria (AT)

  • ATARAX as Hydroxyzine dihydrochloride

Brazil (BR)

Canada (CA)

Cyprus (CY)

  • ATARAX as Hydroxyzine dihydrochloride

Ecuador (EC)

Estonia (EE)

  • ATARAX as Hydroxyzine dihydrochloride

Finland (FI)

  • ATARAX as Hydroxyzine dihydrochloride

France (FR)

  • ATARAX as Hydroxyzine dihydrochloride

Hong Kong (HK)

  • ALLERAX as HYDROXYZINE DIHYDROCHLORIDE
  • ATARAX as Hydroxyzine dihydrochloride
  • CERAX as HYDROXYZINE DIHYDROCHLORIDE
  • POLIZINE as HYDROXYZINE DIHYDROCHLORIDE
  • ROZINE as HYDROXYZINE DIHYDROCHLORIDE
  • VATARAX as HYDROXYZINE DIHYDROCHLORIDE

Japan (JP)

  • ATARAX as Hydroxyzine dihydrochloride

Malta (MT)

  • ATARAX as Hydroxyzine dihydrochloride
  • FENARTIX as HYDROXYZINE DIHYDROCHLORIDE

Mexico (MX)

  • ATARAX as Hydroxyzine dihydrochloride

Poland (PL)

  • ATARAX as Hydroxyzine dihydrochloride
  • COMFORTIN as HYDROXYZINE DIHYDROCHLORIDE

Singapore (SG)

  • ATARAX as Hydroxyzine dihydrochloride
  • HIZIN as HYDROXYZINE DIHYDROCHLORIDE
  • PHYMORAX as HYDROXYZINE DIHYDROCHLORIDE

South Africa (ZA)

  • NEURAX as HYDROXYZINE DIHYDROCHLORIDE

Spain (ES)

  • ATARAX as Hydroxyzine dihydrochloride

  • (combination) DOLODENS as HYDROXYZINE DIHYDROCHLORIDE

Tunisia (TN)

  • ATARAX as Hydroxyzine dihydrochloride

Turkey (TR)

  • ATARAX as Hydroxyzine dihydrochloride
  • HIDRAX as HYDROXYZINE DIHYDROCHLORIDE
  • VALIDOL as HYDROXYZINE DIHYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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