ATARAX Film-coated tablet Ref.[7284] Active ingredients: Hydroxyzine

Source: Υπουργείο Υγείας (CY)  Revision Year: 2023  Publisher: UCB Pharma S.A., 60 ALLÉE DE LA RECHERCHE, BRUSSELS, 1070

Product name and form

ATARAX (Hydroxyzine dihydrochloride) 25 mg film-coated tablet.

ATARAX (Hydroxyzine dihydrochloride) 2 mg/ml syrup.

Pharmaceutical Form

Film-coated tablet: White, oblong, film-coated tablet with bisect line. The tablet can be divided into equal doses.

Syrup: Clear, colourless solution.

Qualitative and quantitative composition

Each film-coated tablet contains 25 mg of hydroxyzine dihydrochloride (Rec. INN).

Each ml of syrup contains 2 mg of hydroxyzine dihydrochloride (Rec. INN).

Excipients with known effect:

Atarax 25 mg film-coated tablets:

Each 25 mg film-coated tablet contains 54.80 mg lactose monohydrate.

Atarax syrup:

Each ml of syrup contains 0.95 mg ethanol.
Each ml of syrup contains 750 mg sucrose.
Each ml of syrup contains 0.30 mg of sodium benzoate (0,048 mg sodium).

For the full list of excipients, see section 6.1.

Active Ingredient

Hydroxyzine is a psycholeptic and anxiolytic agent (ataractic). Hydroxyzine dihydrochloride is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the central nervous system.

List of Excipients

Film-coated tablet at 25 mg (by direct compression):

Core:

Lactose monohydrate
Microcrystalline cellulose
Magnesium stearate
Colloidal anhydrous silica
Purified water

Coat:

Titanium dioxide (E171)
Hydroxy-propyl-methyl-cellulose 2910 5cP
Polyethylene glycol 400
Purified water

Syrup:

Ethanol
Sucrose
Sodium benzoate
Levomenthol
Hazelnut flavour (containing a.o. propylene glycol, vanillin, ethyl vanillin, fenugreek seed extract, lovage oil)
Purified water

Pack sizes and marketing

Atarax 25 mg Film-coated tablets: The film-coated tablets are packed in thermoformed PVC/aluminium "blister" strips. Pack size of 25 tabs.

Atarax 2 mg/ml syrup: The syrup is filled in an amber glass bottle (type III – Ph. Eur.) closed by a polypropylene child-proof screw cap equipped with a polyethylene inner joint. A syringe is included for oral administration (Polyethylene/Polystyrene). Pack size of 200 mL.

Not all pack sizes may be marketed.

Marketing authorization holder

UCB Pharma S.A., 60 ALLÉE DE LA RECHERCHE, BRUSSELS, 1070

Marketing authorization dates and numbers

ATARAX 2 mg/ml syrup: 315
ATARAX 25 mg film-coated tablet: 313

Date of first authorization:

ATARAX 2 mg/ml syrup: 02 March 1971
ATARAX 25 mg film-coated tablet: 02 March 1971

Date of renewal of the authorization:

ATARAX 2 mg/ml syrup: 14 May 2010
ATARAX 25 mg film-coated tablet: 21 September 2010

Drugs

Drug Countries
ATARAX Austria, Canada, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Japan, Malta, Mexico, Poland, Singapore, Tunisia, Turkey

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