Active Ingredient: Naloxone
Naloxone is intended for immediate administration as emergency therapy for known or suspected opioid overdose as manifested by respiratory and/or central nervous system depression in both non-medical and healthcare settings.
Naloxone is indicated in adults and adolescents aged 14 years and over.
Naloxone is not a substitute for emergency medical care.
For this indication, competent medicine agencies globally authorize below treatments:
For:
In case that patient age in years is ≥ 14, nasal, 1.8 milligrams naloxone, 1 to 2 doses in total.
The recommended dose is 1.8 mg administered into one nostril.
In some cases, further doses may be necessary. The appropriate maximum dose of naloxone is situation specific. If the patient does not respond, the second dose should be administered after 2-3 minutes. If the patient responds to the first administration but then relapses again into respiratory depression, the second dose should be administered immediately. Further doses (if available) should be administered in alternate nostrils and the patient should be monitored whilst awaiting arrival of the emergency services. Emergency services may administer further doses according to local guidelines.
Naloxone should be administered as soon as possible to avoid damage to the central nervous system or death.
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