CILOXAN Ophthalmic solution Ref.[10774] Active ingredients: Ciprofloxacin

Source: FDA, National Drug Code (US)  Revision Year: 2020 

3. Indications and Usage

CILOXAN Ophthalmic Solution is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below:

Corneal Ulcers:

Pseudomonas aeruginosa
Serratia marcescens*
Staphylococcus aureus
Staphylococcus epidermidis
Streptococcus pneumoniae
Streptococcus (Viridans Group)*

Conjunctivitis:

Haemophilus influenzae
Staphylococcus aureus
Staphylococcus epidermidis
Streptococcus pneumoniae

* Efficacy for this organism was studied in fewer than 10 infections.

10. Dosage and Administration

Corneal Ulcers

The recommended dosage regimen for the treatment of corneal ulcers is two drops into the affected eye every 15 minutes for the first six hours and then two drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill two drops in the affected eye hourly. On the third through the fourteenth day, place two drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelialization has not occurred.

Bacterial Conjunctivitis

The recommended dosage regimen for the treatment of bacterial conjunctivitis is one or two drops instilled into the conjunctival sac(s) every two hours while awake for two days and one or two drops every four hours while awake for the next five days.

9. Overdosage

A topical overdose of CILOXAN (ciprofloxacin ophthalmic solution) 0.3% may be flushed from the eye(s) with warm tap water.

12. Storage and Handling

Store at 2°C to 25°C (36°F-77°F). Protect from light.

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