Ciprofloxacin

Chemical formula: C₁₇H₁₈FN₃O₃  Molecular mass: 331.342 g/mol  PubChem compound: 2764

Active ingredient description

Ciprofloxacin is a fluoroquinolone antibacterial agent. The bactericidal action of ciprofloxacin results from the inhibition of both type II topoisomerase (DNA-gyrase) and topoisomerase IV, required for bacterial DNA replication, transcription, repair and recombination.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01MA02 Ciprofloxacin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01M Quinolone antibacterials → J01MA Fluoroquinolones
Discover more medicines within J01MA02
S01AE03 S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AE Fluoroquinolones
Discover more medicines within S01AE03
S02AA15 Ciprofloxacin S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives
Discover more medicines within S02AA15
S03AA07 Ciprofloxacin S Sensory organs → S03 Ophthalmological and otological preparations → S03A Antiinfectives → S03AA Antiinfectives
Discover more medicines within S03AA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CIPROFLOXACIN Solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CETRAXAL Ear drops Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CILOXAN Ophthalmic solution FDA, National Drug Code (US) MPI, US: SPL/Old
CIPRO Film-coated tablet / Oral suspension kit FDA, National Drug Code (US) MPI, US: SPL/PLR
CIPROFLOXACIN Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CILOXAN Eye drops, solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CILOXAN Ointment FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 85721-33-1
CAS Substance: 86393-32-0
CAS Substance: 97867-33-9
DrugBank Drug: DB00537
KEGG Drug: D00186
PubChem Compound: 2764
RxNorm Ingredient: 2551
SNOMED-CT Concept: 372840008
Ciprofloxacin (substance)
UNII Identifier: 5E8K9I0O4U
CIPROFLOXACIN

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