Symmetrel Capsules Ref.[2494] Active ingredients: Amantadine

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2011  Publisher: Alliance Pharmaceuticals Ltd Avonbridge House Bath Road Chippenham Wiltshire SN15 2BB

Product name and form

Symmetrel capsules 100mg.

Pharmaceutical Form

Brownish-red, hard gelatin capsules imprinted SYMM in white on both cap and body.

Qualitative and quantitative composition

Amantadine hydrochloride PhEur 100mg.

Active Ingredient Description
Amantadine

Amantadine has been shown to be a low affinity antagonist at the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors. Overactivity of glutamatergic neurotransmission has been implicated in the generation of parkinsonian symptoms. In addition, amantadine specifically inhibits the replication of influenza A viruses at low concentrations.

List of Excipients

Lactose
Polyvinylpyrrolidone
Magnesium stearate
Red iron oxide (E172)
Titanium dioxide (E171)
Gelatin
Monogramming ink S1-7085 White containing Titanium Dioxide (E171), Ammonium Hydroxide 28%, Propylene Glycol (E1520), Simethicone
or SB-0007P White Ink containing: Shellac, Propylene Gylcol, Sodium Hydroxide, Povidone, Titanium Dixoide (E171).

Pack sizes and marketing

Aluminium/PVdC blister packs of 56 capsules.

Marketing authorization holder

Alliance Pharmaceuticals Ltd
Avonbridge House
Bath Road
Chippenham
Wiltshire
SN15 2BB

Marketing authorization dates and numbers

PL16853/0015

26 June 1998

Drugs

Drug Countries
SYMMETREL Australia, Hong Kong, Japan, Malta, Netherlands, New Zealand, Singapore, South Africa

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.