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Imuran Tablets 25mg (2012)

Active ingredients: Azathioprine

Product Name and Form

Imuran tablets 25 mg.

Pharmaceutical form

Tablet.

Qualitative and Quantitative Composition

Orange, round, biconvex, film-coated tablets, impressed ‘GX EL5’ and containing 25 mg Azathioprine BP in each tablet.

Chemical substance
Description
Azathioprine

Azathioprine is a pro-drug of 6-mercaptopurine (6-MP). 6-MP is inactive but acts as a purine antagonist and requires cellular uptake and intracellular anabolism to thioguanine nucleotides (TGNs) for immunosuppression. The TGNs and other metabolites (e.g. 6-methyl-mecaptopurine ribonucleotides) inhibit de novo purine synthesis and purine nucleotide interconversions.

List of excipients

Lactose
Pregelatinised starch
Maize starch
Stearic acid
Magnesium sterate
Methylhydroxylpropyl cellulose
Polyethylene glycol 400
Titanium dioxide (E171)
Iron oxide, yellow (E172), iron oxide, red (E172)
Industrial methylated spirit
Purified water.

Pack sizes and Marketing

Blister strips in a pack.

Pack sizes: 28, 30, 56, 60 and 100 tablets.

Marketing authorization holder
Authorization dates

Aspen Pharma Trading Limited
12/13 Exchange Place
I.F.S.C
Dublin 1
Ireland

20 March 1992

Marketing authorization number:

PL 39699/0004