Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2012 Publisher: Eisai Ltd. European Knowledge Centre Mosquito Way Hatfield Hertfordshire AL10 9SN United Kingdom
Targretin 75 mg soft capsules.
| Pharmaceutical Form |
|---|
|
Soft capsule. Off-white capsule, containing a liquid suspension and imprinted with Targretin. |
Each capsule contains 75 mg of bexarotene.
For a full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Bexarotene |
Bexarotene is a synthetic compound that exerts its biological action through selective binding and activation of the three RXRs: α, β, and γ. Once activated, these receptors function as transcription factors that regulate processes such as cellular differentiation and proliferation, apoptosis, and insulin sensitisation. The exact mechanism of action of bexarotene in the treatment of cutaneous T-cell lymphoma (CTCL) is unknown. |
| List of Excipients |
|---|
|
Capsule content: Macrogol Capsule shell: Gelatin |
High-density polyethylene bottles with child-resistant closures containing 100 capsules.
Eisai Ltd.
European Knowledge Centre
Mosquito Way
Hatfield
Hertfordshire
AL10 9SN
United Kingdom
EU/1/01/178/001
Date of first authorisation: 29 March 2001
Date of latest renewal: 29 March 2006
| Drug | Countries | |
|---|---|---|
| TARGRETIN | Austria, Estonia, Spain, Finland, France, Croatia, Ireland, Italy, Japan, Lithuania, Netherlands, Poland, Romania, United Kingdom, United States |
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