Active ingredients: Chlorambucil
Leukeran Tablets 2 mg.
Film-coated tablet.
Each tablet contains 2 mg of the active ingredient chlorambucil.
Chlorambucil is an aromatic nitrogen mustard derivative which acts as a bifunctional alkylating agent. In addition to interference with DNA replication, chlorambucil induces cellular apoptosis via the accumulation of cytosolic p53 and subsequent activation of an apoptosis promoter.
Tablet Core:
Microcrystalline cellulose
Anhydrous lactose
Colloidal anhydrous silica
Stearic acid
Tablet Film Coating:
Hypromellose
Titanium dioxide
Synthetic yellow iron oxide
Synthetic red iron oxide
Macrogol
Leukeran are brown film-coated, round, biconvex tablets engraved “GX EG3” on one side and “L” on the other, supplied in amber glass bottles with a child resistant closure containing 25 tablets.
Aspen Pharma Trading Limited
12/13 Exchange Place
I.F.S.C
Dublin 1
Ireland
PL 39699/0041
22.06.2006