Active ingredients: Tioguanine

Product name and form

Lanvis 40mg Tablets.

Pharmaceutical Form


Lanvis Tablets are white to off white tablet, round, biconvex scored and imprinting ‘T40’ on upper side, without score and debossing on lower side.

The scoreline is only to facilitate breaking for ease of swallowing and not to divide into equal doses.

Qualitative and quantitative composition

Tablet containing 40 mg tioguanine.

Excipients: Also contains 150mg Lactose Monohydrate

For a full list of excipients, see section 6.1.

Active Ingredient

Tioguanine is a sulphydryl analogue of guanine and behaves as a purine antimetabolite. It is activated to its nucleotide, thioguanylic acid. Tioguanine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. Tioguanine is also incorporated into nucleic acids and DNA (deoxyribonucleic acid) incorporation is claimed to contribute to the agent’s cytotoxicity.

List of Excipients

Lactose monohydrate
Potato starch
Stearic acid
Magnesium stearate

Pack sizes and marketing

Lanvis tablets are supplied in amber (Type III) glass bottles with a polypropylene/HDPE child-resistant closure, containing 25 tablets.

Marketing Authorization Holder
Authorization Dates

Aspen Pharma Trading Limited
3016 Lake Drive
Citywest Business Campus
Dublin 24

Date of first authorisation: 1 April 1979

Date of last renewal: 1 April 2009

Marketing authorization number:

PA 1691/6/1


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