Active ingredients: Tioguanine
Product Name and Form
Lanvis 40mg Tablets.
Lanvis Tablets are white to off white tablet, round, biconvex scored and imprinting ‘T40’ on upper side, without score and debossing on lower side.
The scoreline is only to facilitate breaking for ease of swallowing and not to divide into equal doses.
Qualitative and Quantitative Composition
Tablet containing 40 mg tioguanine.
Excipients: Also contains 150mg Lactose Monohydrate
For a full list of excipients, see section 6.1.
Tioguanine is a sulphydryl analogue of guanine and behaves as a purine antimetabolite. It is activated to its nucleotide, thioguanylic acid. Tioguanine metabolites inhibit de novo purine synthesis and purine nucleotide interconversions. Tioguanine is also incorporated into nucleic acids and DNA (deoxyribonucleic acid) incorporation is claimed to contribute to the agent’s cytotoxicity.
Pack sizes and Marketing
Lanvis tablets are supplied in amber (Type III) glass bottles with a polypropylene/HDPE child-resistant closure, containing 25 tablets.
Aspen Pharma Trading Limited
3016 Lake Drive
Citywest Business Campus
Date of first authorisation: 1 April 1979
Date of last renewal: 1 April 2009